Publications

RPmirDIP: Reciprocal Perspective improves miRNA targeting prediction

MicroRNAs (miRNAs) are short, non-coding RNAs that interact with messenger RNA (mRNA) to accomplish critical cellular activities such …

Gas Prices of America: The Machine-Augmented Crowd-Sourcing Era

Google Street View (GSV) comprises the largest collection of vehicle-based imagery of the natural environment. With high spatial …

Computational Prediction of the Comprehensive SARS-CoV-2 vs. Human Interactome to Guide the Design of Therapeutics

Understanding the disease pathogenesis of the novel coronavirus, denoted SARS-CoV-2, is critical to the development of anti-SARS-CoV-2 …

PIPE4: Fast PPI Predictor for Comprehensive Inter- and Cross-Species Interactomes

The need for larger-scale and increasingly complex protein-protein interaction (PPI) prediction tasks demands that state-of-the-art …

Insights into the suitability of utilizing brown rats (Rattus norvegicus) as a model for healing spinal cord injury with epidermal growth factor and fibroblast growth factor-II by predicting protein-protein interactions

The stimulation of the proliferation and differentiation of neural stem cells (NSCs) offers the possibility of a renewable source of …

Deep learning for critical infrastructure resilience

Ensuring the resiliency of critical infrastructures is essential in modern society, but much of the deployed infrastructure has yet to …

*In Silico* Engineering of Synthetic Binding Proteins from Random Amino Acid Sequences

Synthetic proteins with high affinity and selectivity for a protein target can be used as research tools, biomarkers, and …

PIPE4: Ultra-Fast PPI Predictor for Comprehensive Inter-and Cross-Species Interactomes

Systematic Street View Sampling: High quality annotation of power infrastructure in rural ontario

Google Street View and the emergence of self-driving vehicles afford an unprecedented capacity to observe our planet. Fused with …

Fitting rank order data in the age of context

Rank order data are pervasive in science and in our daily lived experience. With the advent of high performance computing and the …

High quality annotations of power infrastructure in Rural Ontario

We used the Systematic Street View Sampler (S^3) to acquire 18,883 sampled Google Street View images throughout the rural areas of …

Reciprocal perspective for improved protein-protein interaction prediction

All protein-protein interaction (PPI) predictors require the determination of an operational decision threshold when differentiating …

Developing a Real-Time Patient Monitor Data Import System

This paper develops platform agnostic, user-friendly, open source software applications Patient Monitor Data Importer (PMDI) and …

Designing anti-Zika virus peptides derived from predicted human-Zika virus protein-protein interactions

The production of anti-Zika virus (ZIKV) therapeutics has become increasingly important as the propagation of the devastating virus …

Positome: A method for improving protein-protein interaction quality and prediction accuracy

The progressive elucidation of positive protein-protein interactions (PPIs) as wet-lab techniques continue to improve in both …

Identifying Unvaccinated Individuals in Canada: A Predictive Model

Recently, the media and public health officials have become increasingly aware of the rise in anti-vaccine sentiment. Vaccinations have …

Comparison of sequence-and structure-based protein-protein interaction sites

Computational protein-protein interaction (PPI) prediction is a diverse field with multiple paradigms generating insightful interaction …